Metaphyseal chondrodysplasia Schmid type is a type of chondrodysplasia associated with a deficiency of collagen, type X, alpha 1.[2][3][4]
Schmid metaphyseal chondrodysplasia | |
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Other names | MCDS[1] |
This condition is inherited in an autosomal dominant manner. | |
Specialty | Orthopedic |
Unlike other "rickets syndromes", affected individuals have normal serum calcium, phosphorus, and urinary amino acid levels. Long bones are short and curved, with widened growth plates and metaphyses.[5]
It is named for the German researcher F. Schmid, who characterized it in 1949.[6]