The term Metropolitanate of Skopje may refer to:

• Metropolitanate of Skopje, an Eastern Orthodox canonical metropolitanate with seat in the city of Skopje, that historically existed in continuity, under several consequent ecclesiastical jurisdictions.
• Bulgarian Orthodox Metropolitanate of Skopje [bg], an Eastern Orthodox (noncanonical) metropolitanate of the Bulgarian Exarchate, that existed in the second half of 19th century and the beginning of 20th century.
• Macedonian Orthodox Metropolitanate of Skopje [mk], an Eastern Orthodox metropolitanate of the Macedonian Orthodox Church, created in 1967 (noncanonical 1967–2022).
• Metropolis of Skopia, under jurisdiction of the Ecumenical Patriarchate from 1766 to 1920.