Joseph is most famous for playing Walford's first lesbian resident, Della Alexander, in the BBC soap opera EastEnders from 1994–1995.

Other acting credits include:

• As Time Goes By (1994)
• EastEnders (1994–1995)
• Thief takers (1996–1997)
• Dream Team (1998)
• The Bill (2000; 2001)
• So What Now? (2001)
• A Touch of Frost (2002)
• Holby City (2002)
• Space Odyssey: Voyage To The Planets (2004)
• Messiah (2006)
• Perfect Parents (2006)
• Doctors (2007)
• Apparitions (2008)
• Doctors (2012)
• Fast Girls (2012)

• Michelle Joseph at IMDb