Mitoguazone

Summary

Mitoguazone (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in chemotherapy.[1]

Mitoguazone
Clinical data
Other names2-[[(1E)-1-(Diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine
ATC code
Identifiers
  • (2E,2'E)-2,2'-(1E,2E)-propane-1,2-diylidenedihydrazinecarboximidamide
CAS Number
  • 459-86-9 checkY
PubChem CID
  • 5351154
ChemSpider
  • 4508218 ☒N
UNII
  • OD5Q0L447W
KEGG
  • D07258 checkY
ChEBI
  • CHEBI:43996 ☒N
CompTox Dashboard (EPA)
  • DTXSID70861943 Edit this at Wikidata
ECHA InfoCard100.121.515 Edit this at Wikidata
Chemical and physical data
FormulaC5H12N8
Molar mass184.207 g·mol−1
3D model (JSmol)
  • Interactive image
  • C\C(\C=N\NC(N)=N)=N/NC(N)=N
  • InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+ ☒N
  • Key:PKDBCJSWQUOKDO-UHFFFAOYSA-M ☒N
 ☒NcheckY (what is this?)  (verify)

References edit

  1. ^ Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E (1989). "[Mitoguazone (methylglyoxal bis(guanylhydrazone))--its status and prospects]". Archiv für Geschwulstforschung (in German). 59 (2): 135–48. PMID 2655552.