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Morforex

Summary

Morforex (INN; Bo 637), also referable to as N-morpholinoethylamphetamine, is an anorectic which was never marketed.[1][2]

Morforex
Clinical data
ATC code
  • None
Identifiers
  • 4-[2-[(α-Methylphenethyl)amino]ethyl]morpholine
CAS Number
  • 41152-17-4
PubChem CID
  • 3047774
ChemSpider
  • 2310095
UNII
  • O9J6ITY8UX
Chemical and physical data
FormulaC15H24N2O
Molar mass248.370 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(Cc1ccccc1)NCCN2CCOCC2
  • InChI=1S/C15H24N2O/c1-14(13-15-5-3-2-4-6-15)16-7-8-17-9-11-18-12-10-17/h2-6,14,16H,7-13H2,1H3
  • Key:ISEKMORYCCULAL-UHFFFAOYSA-N

It produces amphetamine as an active metabolite.[3]

Synthesis edit

 
Patent:[4]

Amphetamine is reacted with N-Chloroethylmorpholine [3240-94-6] in the presence of IPA solvent.

See also edit

References edit

  1. ^ Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1377–. ISBN 978-0-412-46630-4.
  2. ^ World Health Organization (2000). International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization. ISBN 978-0-11-986227-0.
  3. ^ Goodwin BL (10 November 2004). Handbook of Biotransformations of Aromatic Compounds. CRC Press. pp. 13–. ISBN 978-0-203-64196-5.
  4. ^ FR 2199M, "N-morpholino-1 n-phénylisopropylamino-2 éthane [N-morpholino-1 N-phenylisopropylamino-2 ethane]", published 1963-12-09, assigned to Brevets Pharmaceutiques et Cosmetologiques