Nanchung

Summary

Nanchung is an invertebrate TRP channel that acts to sense mechanical force.[1] Drosophila nanchung mutants show deficits in antennal sensation, including hearing and hygrosensation, and are unable to transduce sound stimuli.[2][3]

References edit

  1. ^ Kim, J; Chung, Y. D.; Park, D. Y.; Choi, S; Shin, D. W.; Soh, H; Lee, H. W.; Son, W; Yim, J; Park, C. S.; Kernan, M. J.; Kim, C (2003). "A TRPV family ion channel required for hearing in Drosophila". Nature. 424 (6944): 81–4. Bibcode:2003Natur.424...81K. doi:10.1038/nature01733. PMID 12819662. S2CID 4426696.
  2. ^ Zhang, W; Yan, Z; Jan, L. Y.; Jan, Y. N. (2013). "Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae". Proceedings of the National Academy of Sciences. 110 (33): 13612–7. Bibcode:2013PNAS..11013612Z. doi:10.1073/pnas.1312477110. PMC 3746866. PMID 23898199.
  3. ^ Lehnert, B. P.; Baker, A. E.; Gaudry, Q; Chiang, A. S.; Wilson, R. I. (2013). "Distinct roles of TRP channels in auditory transduction and amplification in Drosophila". Neuron. 77 (1): 115–28. doi:10.1016/j.neuron.2012.11.030. PMC 3811118. PMID 23312520.