Norvinisterone, sold under the brand names Neoprogestin and Nor-Progestelea, is a progestin and androgen/anabolic steroid (AAS) medication which was used in Europe but is now no longer marketed.[1][2][3][4][5] It is taken by mouth.
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Trade names | Neoprogestin, Nor-Progestelea |
Other names | Vinylnortestosterone; SC-4641; 17α-Vinyl-19-nortestosterone; 17α-Vinylestr-4-en-17β-ol-3-one |
Routes of administration | By mouth |
Drug class | Progestogen; Progestin; Androgen; Anabolic steroid |
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Chemical and physical data | |
Formula | C20H28O2 |
Molar mass | 300.442 g·mol−1 |
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Melting point | 169 to 171 °C (336 to 340 °F) [1] |
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Norvinisterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone.[2] It has androgenic activity.[6]
Norvinisterone was synthesized in 1953.[2] It is no longer available.[7]
Norvinisterone was used in hormonal contraception to prevent pregnancy.[1][3]
Norvinisterone is a progestogen.[2][8][5] It appears to be quite androgenic, with about one-third and one-fifth of the androgenic and anabolic activity, respectively, of nandrolone in animal bioassays.[6] However, it has also been reported to have little anabolic activity.[9]
Norvinisterone, also known as 17α-vinyl-19-nortestosterone or as 17α-vinylestr-4-en-17β-ol-3-one, is a synthetic estrane steroid and a derivative of testosterone and 19-nortestosterone.[2] Analogues of norvinisterone include the progestin norgesterone and the AAS vinyltestosterone.[2]
Norvinisterone was synthesized in 1953[2] and was studied in humans by 1960.[8]
Norvinisterone is the generic name of the drug and its INN .[2] It is also known as vinylnortestosterone and is known by its developmental code name SC-4641.[2][1]
Norvinisterone was marketed under the brand names Neoprogestin and Nor-Progestelea by Syntex.[2][1]
Norgesterone is no longer marketed and hence is no longer available in any country.[7]