O-1918 is a synthetic compound related to cannabidiol, which is an antagonist at two former orphan receptors GPR18 and GPR55, that appear to be related to the cannabinoid receptors. O-1918 is used in the study of these receptors, which have been found to be targets for a number of endogenous and synthetic cannabinoid compounds, and are thought to be responsible for most of the non-CB1, non-CB2 mediated effects that have become evident in the course of cannabinoid research.[1][2][3][4][5]
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Formula | C19H26O2 |
Molar mass | 286.415 g·mol−1 |
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Subsequent research by using electrophysiological approach has shown that O-1918 is a potent BKCa channel inhibitor.[6][7][8]