OR12D2 Knowpia

OR12D2
Identifiers
Aliases	OR12D2, DJ994E9.8, HS6M1-20, olfactory receptor family 12 subfamily D member 2 (gene/pseudogene), olfactory receptor family 12 subfamily D member 2
External IDs	MGI: 2177484 HomoloGene: 133728 GeneCards: OR12D2
Gene location (Human)
Chr.	Chromosome 6 (human)
End	29,398,008 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,615,204 bp
RNA expression pattern
	Top expressed in
	hypothalamus; ; hippocampus proper; ; caudate nucleus; ; temporal lobe; ; amygdala; ; Brodmann area 9; ; nucleus accumbens;
	Top expressed in
	spleen;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26529
	258831
	ENSG00000280236
	ENSMUSG00000092077
	P58182
	Q920Z0
	NM_013936
	NM_146834
	NP_039224
	NP_667045
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor, family 12, subfamily D, member 2, also known as OR12D2, is a protein which in humans is encoded by the OR12D2 gene.^[5]

Function edit

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000280236 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000092077 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR12D2 olfactory receptor, family 12, subfamily D, member 2".