OR2H2 Knowpia

OR2H2
Identifiers
Aliases	OR2H2, FAT11, OLFR2, OLFR42B, OR2H3, dJ271M21.2, hs6M1-12, olfactory receptor family 2 subfamily H member 2
External IDs	OMIM: 600578 MGI: 2177473 HomoloGene: 68546 GeneCards: OR2H2
Gene location (Human)
Chr.	Chromosome 6 (human)
End	29,590,500 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,399,391 bp
RNA expression pattern
	Top expressed in
	putamen; ; nucleus accumbens; ; caudate nucleus; ; temporal lobe; ; amygdala; ; hippocampus proper; ; hypothalamus; ; superior frontal gyrus; ; dorsolateral prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	blastocyst; ; bone marrow; ; conceptus; ; female reproductive system; ; placenta;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; olfactory receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	defense response; mating; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7932
	258469
	ENSG00000204657
	ENSMUSG00000056600
	O95918
	n/a
	NM_007160
	NM_146477
	NP_009091
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2H2 is a protein that in humans is encoded by the OR2H2 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000204657 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056600 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR2H2 olfactory receptor, family 2, subfamily H, member 2".