OR2M7 Knowpia

OR2M7
Identifiers
Aliases	OR2M7, OR1-58, olfactory receptor family 2 subfamily M member 7
External IDs	OMIM: 618509 HomoloGene: 133839 GeneCards: OR2M7
Gene location (Human)
Chr.	Chromosome 1 (human)
End	248,324,568 bp
RNA expression pattern
	Top expressed in
	reproductive system; ; reproductive organ; ; gonad; ; male reproductive system; ; testicle;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; olfactory receptor activity; G protein-coupled receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	391196
	n/a
	ENSG00000177186
	n/a
	Q8NG81
	n/a
	NM_001004691
	n/a
	NP_001004691
	n/a
	Wikidata
View/Edit Human

Olfactory receptor 2M7 is a protein that in humans is encoded by the OR2M7 gene.^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[3]

Ligands edit

Agonists include:^[4]

(-)-Citronellol
Geraniol

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000177186 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR2M7 olfactory receptor, family 2, subfamily M, member 7".
^ Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009). "Odor coding by a Mammalian receptor repertoire". Science Signaling. 2 (60): ra9. doi:10.1126/scisignal.2000016. PMC 2774247. PMID 19261596.