OR2T1 Knowpia

OR2T1
Identifiers
Aliases	OR2T1, OR1-25, olfactory receptor family 2 subfamily T member 1
External IDs	MGI: 109304 HomoloGene: 74028 GeneCards: OR2T1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	248,408,020 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	8,146,935 bp
RNA expression pattern
	Top expressed in
	brain; ; prefrontal cortex; ; cerebral cortex; ; multicellular organism;
	Top expressed in
	hypothalamus; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26696
	18330
	ENSG00000275244; ENSG00000273508; ENSG00000175143
	ENSMUSG00000072707
	O43869
	n/a
	NM_030904
	NM_147027
	NP_112166
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2T1 is a protein that in humans is encoded by the OR2T1 gene.^[5]^[6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[6]

References edit

^ ^a ^b ^c ENSG00000273508, ENSG00000175143 GRCh38: Ensembl release 89: ENSG00000275244, ENSG00000273508, ENSG00000175143 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000072707 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
^ ^a ^b "Entrez Gene: OR2T1 olfactory receptor, family 2, subfamily T, member 1".