OR4F3 Knowpia

OR4F3
Identifiers
Aliases	OR4F3, olfactory receptor family 4 subfamily F member 3
External IDs	MGI: 3031137 HomoloGene: 88429 GeneCards: OR4F3
Gene location (Human)
Chr.	Chromosome 5 (human)
End	181,368,262 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	111,650,685 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; duodenum; ; rectum; ; placenta; ; islet of Langerhans; ; tibial nerve; ; right lobe of thyroid gland; ; myometrium; ; temporal lobe; ; amygdala;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26683
	258397
	ENSG00000230178
	ENSMUSG00000093804
	Q6IEY1
	A2AVW1
	NM_001005224
	NM_146402
	NP_001005224; NP_001005221; NP_001005277
	NP_666514
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 4F3/4F16/4F29 is a protein that in humans is encoded by the OR4F3 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000230178 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000093804 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR4F3 olfactory receptor, family 4, subfamily F, member 3".