OR52L1

Summary

Olfactory receptor 52L1 is a protein that in humans is encoded by the OR52L1 gene.[5]

OR52L1
Identifiers
AliasesOR52L1, OR11-50, olfactory receptor family 52 subfamily L member 1, olfactory receptor family 52 subfamily L member 1 (gene/pseudogene)
External IDsMGI: 3030519 HomoloGene: 66455 GeneCards: OR52L1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001005173

NM_001011857

RefSeq (protein)

NP_001005173

n/a

Location (UCSC)Chr 11: 5.99 – 5.99 MbChr 7: 104.83 – 104.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183313 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047794 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR52L1 olfactory receptor, family 52, subfamily L, member 1".

Further reading edit

  • Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links edit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.