OR6C3

Summary

Olfactory receptor 6C3 is a protein that in humans is encoded by the OR6C3 gene.[5]

OR6C3
Identifiers
AliasesOR6C3, OST709, olfactory receptor family 6 subfamily C member 3
External IDsMGI: 3030637 HomoloGene: 105153 GeneCards: OR6C3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_054104
NM_001388498

NM_146554

RefSeq (protein)

NP_473445

NP_666765

Location (UCSC)Chr 12: 55.33 – 55.33 MbChr 10: 129.53 – 129.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000205329 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046041 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR6C3 olfactory receptor, family 6, subfamily C, member 3".

Further reading edit

  • Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
  • Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi:10.1038/nature04569. PMID 16541075.

External links edit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.