OR8B12 Knowpia

OR8B12
Identifiers
Aliases	OR8B12, OR11-317, olfactory receptor family 8 subfamily B member 12
External IDs	MGI: 3030708 HomoloGene: 17377 GeneCards: OR8B12
Gene location (Human)
Chr.	Chromosome 11 (human)
End	124,545,333 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	37,659,890 bp
RNA expression pattern
	Top expressed in
	testicle; ; multicellular organism;
	Top expressed in
	secondary oocyte; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; odorant binding; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	219858
	258882
	ENSG00000170953
	ENSMUSG00000063350
	Q8NGG6
	Q7TRE6
	NM_001005195
	NM_146882
	NP_001005195
	NP_667093
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 8B12 is a protein that in humans is encoded by the OR8B12 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170953 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063350 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR8B12 olfactory receptor, family 8, subfamily B, member 12".