OR8B4 Knowpia

OR8B4
Identifiers
Aliases	OR8B4, OR11-315, OR8B4P, olfactory receptor family 8 subfamily B member 4 (gene/pseudogene), olfactory receptor family 8 subfamily B member 4
External IDs	MGI: 3030712 HomoloGene: 17395 GeneCards: OR8B4
Gene location (Human)
Chr.	Chromosome 11 (human)
End	124,424,871 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	37,833,770 bp
RNA expression pattern
	Top expressed in
	blood; ; multicellular organism;
	Top expressed in
	secondary oocyte;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; odorant binding; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	283162
	258794
	ENSG00000280090
	ENSMUSG00000066747
	Q96RC9
	n/a
	NM_001005196
	NM_146798
	NP_001005196
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 8B4 is a protein that in humans is encoded by the OR8B4 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000280090 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066747 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR8B4 olfactory receptor, family 8, subfamily B, member 4".