OR8K5

Summary

Olfactory receptor 8K5 is a protein that in humans is encoded by the OR8K5 gene.[5]

OR8K5
Identifiers
AliasesOR8K5, OR11-174, olfactory receptor family 8 subfamily K member 5
External IDsMGI: 3030887 HomoloGene: 74197 GeneCards: OR8K5
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001004058

NM_001177857

RefSeq (protein)

NP_001004058

NP_001171328

Location (UCSC)Chr 11: 56.16 – 56.16 MbChr 2: 86.14 – 86.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181752 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075192 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR8K5 olfactory receptor, family 8, subfamily K, member 5".

Further reading edit

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links edit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.