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Omethoate

Summary

Omethoate (C5H12NO4PS) is a systemic organophosphorous insecticide and acaricide available as a soluble concentrate. It is used to control insects and mites in horticulture and agriculture, as well as in the home garden.

Omethoate
Names
Preferred IUPAC name
O,O-Dimethyl S-[2-(methylamino)-2-oxoethyl] phosphorothioate
Other names
Dimethoxon
O,O-Dimethyl S-methylcarbamoylmethyl phosphorothioate
Identifiers
  • 1113-02-6 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:38730 checkY
ChEMBL
  • ChEMBL2270068 ☒N
ChemSpider
  • 13574 checkY
ECHA InfoCard 100.012.907 Edit this at Wikidata
KEGG
  • C18662 checkY
  • 14210
UNII
  • 28U28EWE79 checkY
  • DTXSID4037580 Edit this at Wikidata
  • InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) checkY
    Key: PZXOQEXFMJCDPG-UHFFFAOYSA-N checkY
  • InChI=1/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)
    Key: PZXOQEXFMJCDPG-UHFFFAOYAZ
  • O=C(NC)CSP(=O)(OC)OC
Properties
C5H12NO4PS
Molar mass 213.19 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Omethoate works by inhibiting the enzyme acetylcholinesterase. This inhibition over-stimulattes parts of the nervous system that rely on acetylcholine to transmit nerve impulses. [1]

It is an irritant to the skin and mucous membranes. Its toxicity and hazard potential are still under review because of concerns about its safety.[2] Additionally, it cannot be used on food products.

The acceptable daily intake (ADI) has been amended from 0.0003 to 0.0004 mg/kg bw [1]

Other names edit

  • Folimat - Registered trademark.

Footnotes edit

  1. ^ a b "Omethoate Proposed Regulatory Information" (PDF). p. 2,8. Retrieved 9 February 2023.
  2. ^ Australian Government. Australian Pesticides and Veterinary Medicines Authority.

External links edit

  • Omethoate review - updated 22 August 2008.
  • Omethoate in the Pesticide Properties DataBase (PPDB)