Onorato Caetani may refer to:

• Onorato Caetani (died 1400), Neapolitan statesman, senator of Rome
• Onorato Caetani (1414–1491) [it], Neapolitan statesman and art patron
• Onorato Caetani (died 1528) [it], Neapolitan nobleman
• Onorato Caetani (1542–1592) [it], Italian mercenary
• Onorato Caetani (1742–1797), Italian scholar and art patron
• Onorato Caetani (1842–1917), Italian politician, president of the Italian Geographical Society