Ornidazole is an antibiotic used to treat protozoan infections.[1]: 1368 A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin.[2]
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Trade names | Xynor |
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Routes of administration | Oral |
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Metabolism | Via liver[1]: 1356 |
Elimination half-life | 12-13 hours[1]: 1356 |
Excretion | Urine (63%) and Feces (22%) |
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ECHA InfoCard | 100.037.099 |
Chemical and physical data | |
Formula | C7H10ClN3O3 |
Molar mass | 219.63 g·mol−1 |
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Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated;[1]: 1368 however there are concerns of lower relative efficacy.[3]
It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities.[4]: 1261 has also been investigated for use in Crohn's disease after bowel resection.[5]