OrthoFinder is a command-line software tool for comparative genomics.[1][2] OrthoFinder determines the correspondence between genes in different organisms (also known as orthology analysis). This correspondence provides a framework for understanding the evolution of life on Earth, and enables the extrapolation and transfer of biological knowledge between organisms.
Original author(s) | David Emms Steven Kelly |
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Developer(s) | David Emms |
Initial release | 2015 |
Repository | github |
Written in | Python |
Operating system | Linux |
Type | Bioinformatics |
License | GNU GPL v3 |
Website | github |
OrthoFinder takes FASTA files of protein sequences as input (one per species) and as output provides:
As of August 2021, the tool has been referenced by more than 1500 published studies.[3]