Oxiconazole

Summary

Oxiconazole (trade names Oxistat in the US, Oxizole in Canada) is an antifungal medication typically administered in a cream or lotion to treat skin infections, such as athlete's foot, jock itch and ringworm. It can also be prescribed to treat the skin rash known as tinea versicolor, caused by systemic yeast overgrowth (Candida spp.).

Oxiconazole
Clinical data
Trade namesOxistat, Oxizole
AHFS/Drugs.comMonograph
MedlinePlusa689004
ATC code
Identifiers
  • (E)-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene] [(2,4-dichlorophenyl)methoxy]amine
CAS Number
  • 64211-46-7 checkY
PubChem CID
  • 5361463
DrugBank
  • DB00239 checkY
ChemSpider
  • 4514745 checkY
UNII
  • RQ8UL4C17S
KEGG
  • D00885 checkY
ChEBI
  • CHEBI:7825 ☒N
ChEMBL
  • ChEMBL1262 ☒N
CompTox Dashboard (EPA)
  • DTXSID8040690 Edit this at Wikidata
Chemical and physical data
FormulaC18H13Cl4N3O
Molar mass429.12 g·mol−1
3D model (JSmol)
  • Interactive image
  • Clc3ccc(/C(=N\OCc1ccc(Cl)cc1Cl)Cn2ccnc2)c(Cl)c3
  • InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18- checkY
  • Key:QRJJEGAJXVEBNE-MOHJPFBDSA-N checkY
 ☒NcheckY (what is this?)  (verify)

It was patented in 1975 and approved for medical use in 1983.[1]

See also edit

References edit

  1. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 503. ISBN 9783527607495.

External links edit

  • MedlinePlus - Oxiconazole