The San Diego Padres are a Major League Baseball team based in San Diego, California.

Padres may also refer to

• Padres workers at the Spanish missions in California
• PADRES, a Chicano priests' organization
• Tucson Padres, a minor league baseball team in Tucson, Arizona
• San Diego Padres (PCL), a former minor league franchise in the Pacific Coast League
• Padres FC, a football club in Australia
• PADReS, a scientific group at the FERMI free electron facility in Trieste (Italy)