Pentre Gwynfryn is a village in the Ardudwy area of Gwynedd, Wales, about 1 mile (1.6 km) east of Llanbedr. The village is at the confluence of the River Artro and the River Cwmnantcol.

Pentre Gwynfryn
The chapel at Pentre Gwynfryn
Pentre Gwynfryn Location within Gwynedd
OS grid reference	SH596270
Community	Llanbedr
Principal area	Gwynedd
Preserved county	Gwynedd
Country	Wales
Sovereign state	United Kingdom
Post town	HARLECH
Postcode district	LL46
Dialling code	01341
Police	North Wales
Fire	North Wales
Ambulance	Welsh
UK Parliament	Dwyfor Meirionnydd
Senedd Cymru – Welsh Parliament	Dwyfor Meirionnydd
List of places UK Wales Gwynedd 52°49′23″N 4°05′02″W / 52.823°N 4.084°W / 52.823; -4.084

The inside of the village's chapel (Capel Salem) was made famous by the painter Sydney Curnow Vosper, whose 1908 work Salem features a member of the congregation, Siân Owen, in traditional Welsh costume. The folds around the left arm of her richly rembroidered cloak are supposed to form the face of the devil, who has taken over the proud woman.^{[citation needed]} A more obvious devil's face is seen peering in through the window. The painting hangs in the Lady Lever Art Gallery at Port Sunlight on the Wirral.