Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class.[1] It is a congener and ring-opened analogue of phenytoin (a hydantoin),[2][3] and is structurally related to the barbiturates and to other hydantoins.[4] Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity.[2][3]
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Trade names | Phenurone |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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Elimination half-life | 22–25 hours |
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ECHA InfoCard | 100.000.519 |
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Formula | C9H10N2O2 |
Molar mass | 178.191 g·mol−1 |
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