The Pine Bluff Metropolitan Statistical Area, as defined by the United States Census Bureau, is a three-county region in southeast Arkansas, anchored by the city of Pine Bluff. As of the 2010 census, the MSA had a population of 100,258.^[1] The metro area's population declined by 12.47% between 2010 and 2020, more than any other metropolitan area in the United States. It is also a component of the larger Little Rock-North Little Rock, AR Combined Statistical Area which had 902,443 people in the census estimates of 2014.