Pivoxazepam

Summary

Pivoxazepam is a drug which is a benzodiazepine derivative. It is the pivalate (2,2-dimethylpropanoate) ester of oxazepam.[1] It has sedative and anxiolytic actions like those of other benzodiazepines. Compared to its parent drug, oxazepam, pivoxazepam is more rapidly absorbed and slightly more sedative.

Pivoxazepam
Identifiers
  • (RS)-7-Chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl pivalate
CAS Number
  • 55299-10-0 ☒N
PubChem CID
  • 68722
ChemSpider
  • 61972 checkY
UNII
  • F4ER8Z6Q3U
ChEMBL
  • ChEMBL357440 checkY
Chemical and physical data
FormulaC20H19ClN2O3
Molar mass370.83 g·mol−1
3D model (JSmol)
  • Interactive image
ChiralityRacemic mixture
  • Clc3cc\1c(NC(=O)C(OC(=O)C(C)(C)C)/N=C/1c2ccccc2)cc3
  • InChI=1S/C20H19ClN2O3/c1-20(2,3)19(25)26-18-17(24)22-15-10-9-13(21)11-14(15)16(23-18)12-7-5-4-6-8-12/h4-11,18H,1-3H3,(H,22,24) checkY
  • Key:FTJLKTBLZOULCL-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

See also edit

References edit

  1. ^ Sánchez MC, Colomé J, Gelpí E (November 1976). "Electron capture and multiple ion detection of benzodiazepine esters in pharmacokinetic studies". Journal of Chromatography. 126: 601–13. doi:10.1016/s0021-9673(01)84105-4. PMID 10316.