From 1972 to the early 1980s, physical science teacher and athletic advisor Eddie Fischer sexually abused at least twenty students at Porter-Gaud and nineteen at other Charleston, SC schools. In 1982, in response to complaints about Fischer's sexual behavior, the administration of Porter-Gaud asked Fischer to resign. Both Principal James Bishop Alexander and Headmaster Berkeley Grimball then helped Fischer to get a job at another private school, where he continued to abuse. In April 1999, Fischer was sentenced to twenty years in prison for thirteen sexual-abuse charges. ^[1]

In October 2000, following Fischer's incarceration, a court determined that former Principal James Bishop Alexander and Headmaster Berkeley Grimball knew of the ongoing abuse by Fischer.^[2] The jury deemed both negligent in stopping the abuse. Neither Principal Alexander nor Headmaster Grimball were ultimately convicted, as each died prior to the court concluding.^[2] However, the court awarded the plaintiffs $105 million.

The scandal was the subject of a 2018 documentary, What Haunts Us. The film suggests the suicides of six graduates of the 1979 class were due to the mental impact of being sexually abused by Fischer.^[2] The colluding culture of the school with board members ignoring persistent pleas to be heard by one victim, who wrote to all the board members who never responded or discussed it, revealed that these young victims were trapped within a culture where the surface of respectability had to be maintained at all costs.^[2] Porter-Gaud school did make a public apology but not to the victims themselves.^[3]

• John Buse – President of the American Diabetes Association
• Octavus Roy Cohen – writer
• Stephen Colbert – comedian, host of The Late Show
• Joel Derfner – author, musical theater composer
• Shepard Fairey – artist
• Jack Hitt – writer and contributing editor for This American Life, Harper's and The New York Times Magazine; previously wrote for Rolling Stone and Wired
• Benjamin Hutto - Director of Choral Activities and Director of Performing Arts at St. Albans School for Boys and the National Cathedral School for Girls in Washington D.C., organist for St. John's Episcopal Church - "the Nation's Church"
• Josiah-Jordan James - basketball player for the Tennessee Volunteers
• George P. Kent - diplomat, Deputy Assistant Secretary of State for European and Eurasian Affairs
• Sallie Krawcheck – former CFO of Citigroup Inc.; former CEO of Smith Barney; member of the board of directors at Dell Computers, Head of Bank of America's Global Wealth Management division
• George Swinton Legaré – member of the United States House of Representatives, prominent Charleston lawyer
• Burnet R. Maybank – Depression-era mayor of Charleston, Governor of South Carolina and United States Senator
• Khris Middleton – NBA Championship winner for the Milwaukee Bucks, formerly of the Detroit Pistons; Olympic Gold Medalist
• Ovie Mughelli – NFL football player
• Aaron Nesmith - NBA basketball player for the Indiana Pacers
• Vic Rawl – Democratic candidate for U.S. Senate; received national attention after losing to Alvin Greene
• Archibald Rutledge – South Carolina poet laureate
• Sonny Seiler – attorney, owner of Uga, the University of Georgia bulldog mascot
• Charles P. Summerall – United States Army general, Army Chief of Staff
• Kurt W. Tidd – United States Navy Admiral Commander U.S. Southern Command

• Hervey Allen – author from Pennsylvania; works include: Anthony Adverse, Israfel, Action at Aquila, and The Forest and the Fort
• DuBose Heyward – author best known for his 1924 novel Porgy; co-author of the non-musical play adapted from the novel, which became the foundation of George Gershwin's opera Porgy and Bess
• Benjamin Hutto – music director and choirmaster at the school during the 70s through the 90s, during which time the Porter-Gaud Choir recorded several albums
• Wyndham Meredith Manning – member of the South Carolina House of Representatives

• Charleston Arsenal, the original site of Porter Military Academy^{[citation needed]}