Quick Draw was usually depicted as a sheriff in a series of short films set in the Old West. Quick Draw was often accompanied by his deputy, a Mexican burro called Baba Looey (also voiced by Daws Butler), who spoke with a Mexican accent and called his partner "Queeks Draw".^[14] In the Spanish American version, Quick Draw is named Tiro Loco McGraw, while Baba Looey is named Pepe Trueno. In the Brazilian version, Quick Draw speaks in a Portuguese accent, which along with his Hispanized name (Pepe Legal) would suggest he was either a Texan-American or Mexican cowboy.

Quick Draw satirized the westerns that were popular among the American public at the time. His character was well-intentioned, but somewhat dim. His main catchphrases were "Hold on there!" and "I'll do the thin'in' around here and don't you forget it!" Also if he got hurt he would often say "Ooooh that smarts!" One of the main running gags in the shorts was him accidentally shooting himself with his own six-shooter.

Another featured character was Snuffles, the bloodhound dog that would point to his mouth and "ah-ah-ah-" when he wanted a biscuit, then hug himself, leap up in the air, and float back down after having eaten one. In A Pup Named Scooby-Doo, Scooby follows the same foil as Snuffles when he eats a Scooby snack.^[15]

Quick Draw was himself a horse caricature that walked on two legs like a human (as did Baba Looey), and had "hands" that were hooves with thumbs and could hold objects such as guns. This enabled the show's producers to depict him riding into town on a realistic horse, and as seen in the show's opening credits, driving a stagecoach pulled by a whole team of realistic horses. This aspect was made light of in the 1980s made-for-television film The Good, the Bad, and Huckleberry Hound, which featured Quick Draw.

In certain cases, Quick Draw would also assume the identity of the Spanish masked vigilante El Kabong (a spoof of Zorro).^[16] His introduction went as follows – "Of all the heroes in legend and song, there's none as brave as El Kabong". As El Kabong, Quick Draw would attack his foes by swooping down on a rope with the war cry "OLÉ!" and hitting them on the head with an acoustic guitar (after shouting "KABOOOOOONG!"), which is always referred to as a "kabonger", producing a distinctive kabong sound and usually destroying the guitar in the process. The "guitar" was usually drawn as a four strung cuatro. On the cartoon's soundtrack, the "kabong" sound effect was produced by a Foley artist striking the detuned open strings of a cheap acoustic guitar. Comedian Kenny Moore received the nickname of "El Kabong" on some websites due to his infamous assault of a heckler with the guitar he played as part of his act.^[17]

• Quick Draw McGraw occasionally appeared in other Hanna-Barbera productions, including 1973's Yogi's Gang, 1977–1978's Laff-A-Lympics, a celebrity roast honoring Fred Flintstone on the TV special Hanna-Barbera's All-Star Comedy Ice Revue (1978) and the 1979 TV special Casper's First Christmas, and in an episode from the short-lived 1978 series Yogi's Space Race.
• Quick Draw McGraw appears in Yogi Bear's All Star Comedy Christmas Caper, voiced again by Daws Butler.^[18]
• Quick Draw McGraw and Baba Looey appear in The Yogi Bear Show episode "Yogi's Birthday Party".
• Quick Draw McGraw appears in Yogi's Treasure Hunt.
• Quick Draw McGraw appears in the "Fender Bender 500" segment of Wake, Rattle, and Roll, voiced by Greg Burson, while Baba Looey is voiced by Neil Ross.
• Quick Draw McGraw and Baba Looey appear in the Yo Yogi! episode "Yippee Yo, Yogi!", voiced again by Greg Burson, while Baba Looey is voiced by Henry Polic II.
• Quick Draw McGraw makes a cameo appearance in the Samurai Jack episode "Couple on a Train", voiced again by Greg Burson.^[18]
• Quick Draw McGraw appears in the Robot Chicken episode "Laff-A-Munich", voiced by Seth Green.
• Quick Draw McGraw appears in The Simpsons episode "Million Dollar Abie".
• Quick Draw McGraw appears in the I Am Weasel episode "I Am My Lifetime".
• Quick Draw McGraw appears in the Class of 3000 episode "Home", voiced by Tom Kenny.^[18]
• Quick Draw McGraw and Baba Looey appear in the South Park episode "Imaginationland Episode III".
• Quick Draw McGraw appears in Harvey Birdman, Attorney at Law, voiced by Maurice LaMarche.^[18]
• Quick Draw's dog Snuffles appears in the Johnny Bravo episode "Double Vision".
• Quick Draw McGraw appears in the final issue of Exit, Stage Left!: The Snagglepuss Chronicles. In the same issue, he was also portrayed as Huckleberry Hound's lover.
• Quick Draw McGraw appears in the Wacky Races episode "Much Ado About Wacky", voiced by Billy West.^[18]
• Quick Draw McGraw and Baba Looey make cameo appearances in the Animaniacs episode "Suffragette City".
• Quick Draw McGraw appears in Jellystone!,^[19] voiced by Bernardo de Paula.^[8] This version is a Hispanic superhero and teacher who is an enemy of The Banana Splits and wields a guitar named Susan (voiced by Melissa Villaseñor).^[20]
• Quick Draw McGraw appears in the Teen Titans Go! episode "Warner Bros. 100th Anniversary".^[21]

• Quick Draw was the mascot for Sugar Smacks in the early 1960s.
• Quick Draw made a cameo in a MetLife commercial in 2012.

• There are references to "El Kabong" in the TV series The Critic – Jay Sherman's father, Franklin Sherman, imitates El Kabong, swooping from chandeliers dressed similar to Zorro and hitting people over the head with a guitar.
• In the professional wrestling world, the name "El Kabong" was used by then-Extreme Championship Wrestling commentator Joey Styles to describe when a popular ECW wrestler, New Jack, used an acoustic guitar as a weapon during a match. The act is also used by former World Wrestling Federation employee The Honky Tonk Man, former enhancement talent Quick Draw Rick McGraw, former Total Nonstop Action Wrestling Vice President and wrestler Jeff Jarrett, and current World Wrestling Entertainment wrestler Elias.
• Noted radio producer Gary Dell'Abate, who has worked for radio "shock jock" Howard Stern since the early 1980s, has been nicknamed "Baba Booey" for many years, after a mispronunciation of Quick Draw McGraw's sidekick, Baba Looey. "Baba Booey" became a catchphrase for Howard Stern fans for decades, usually shouted out in a large crowd.

• McFarlane Toys produced a figure of Quick Draw McGraw as El Kabong as part of their Hanna-Barbera toy line.
• In 1991, Hi-Tec Software published a licensed Quick Draw McGraw video game.

Quick Draw McGraw is referred to in Busta Rhymes' songs "So Hardcore" and "Everything Remains Raw". He is also referred to in MF Doom's Viktor Vaughn song "Modern Day Mugging". Lil Wayne refers to Quick Draw McGraw in his songs "Fireman" and "What's Wrong With Them?" Quick Draw McGraw is also referred to in House of Pain's song "Boom Shalock Lock Boom (Butch Vig Mix)". The song appeared on the EP, Shamrocks and Shenanigans. The Game's "One Blood (Remix)" refers to Quick Draw McGraw.

In the English versions of the Nintendo DS, Android, and iOS versions of Dragon Quest IV, one of Tsarevna Alena's tournament opponents is named Quick Draw McGore.^[22]

• List of fictional horses

• Quick Draw McGraw at Don Markstein's Toonopedia. Archived from the original on November 4, 2016