RAM-378 Knowpia

RAM-378
Identifiers
	IUPAC name 3,6,14-trihydroxy-4,5α-epoxy-17-(2-phenylethyl)morphinan;
CAS Number	4778-96-5 ;
PubChem CID	5492826;
ChemSpider	4591168 ;
UNII	JD4S8J3CMK;
CompTox Dashboard (EPA)	DTXSID70963936 ;
Chemical and physical data
Formula	C24H27NO4
Molar mass	393.483 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CCC6=CC=CC=C6)[C@H]([C@H]1O)OC5=C(C=C4)O)O;
	InChI InChI=1S/C24H27NO4/c26-17-7-6-16-14-19-24(28)10-8-18(27)22-23(24,20(16)21(17)29-22)11-13-25(19)12-9-15-4-2-1-3-5-15/h1-7,18-19,22,26-28H,8-14H2/t18-,19+,22-,23-,24+/m0/s1; Key:GAHRZWMAHDWVCL-VKJMTUIMSA-N;
	(verify)

RAM-378^[1](7,8-Dihydro-14-hydroxy-N-phenethylnormorphine) is an opioid analgesic. It is the N-phenethyl derivative of hydromorphinol.

References edit

^ Ben Haddou T, Béni S, Hosztafi S, Malfacini D, Calo G, Schmidhammer H, Spetea M (2014). "Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity". PLOS ONE. 9 (6): e99231. Bibcode:2014PLoSO...999231B. doi:10.1371/journal.pone.0099231. PMC 4053365. PMID 24919067.

Identifiers

IUPAC name 3,6,14-trihydroxy-4,5α-epoxy-17-(2-phenylethyl)morphinan
CAS Number	4778-96-5^Y
PubChem CID	5492826
ChemSpider	4591168^Y
UNII	JD4S8J3CMK
CompTox Dashboard (EPA)	DTXSID70963936
Chemical and physical data
Formula	C₂₄H₂₇NO₄
Molar mass	393.483 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CCC6=CC=CC=C6)[C@H]([C@H]1O)OC5=C(C=C4)O)O
InChI InChI=1S/C24H27NO4/c26-17-7-6-16-14-19-24(28)10-8-18(27)22-23(24,20(16)21(17)29-22)11-13-25(19)12-9-15-4-2-1-3-5-15/h1-7,18-19,22,26-28H,8-14H2/t18-,19+,22-,23-,24+/m0/s1 Key:GAHRZWMAHDWVCL-VKJMTUIMSA-N
(verify)