Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauvolfia and Corynanthe (including Pausinystalia).[1] It is a stereoisomer of yohimbine.[1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac.[1]
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Routes of administration | Oral |
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ECHA InfoCard | 100.004.553 |
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Formula | C21H26N2O3 |
Molar mass | 354.450 g·mol−1 |
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Rauwolscine acts predominantly as a α2-adrenergic receptor antagonist.[2][3] It has also been shown to function as a 5-HT1A receptor partial agonist and 5-HT2A and 5-HT2B receptor antagonist.[4][5][6]