Robert Glaeser

Summary

Robert Martin Glaeser (born July 20, 1937, in Kenosha, Wisconsin) is an American biochemist. He is a professor emeritus of Biochemistry, Biophysics and Structural Biology at the University of California, Berkeley and a faculty scientist at Lawrence Berkeley National Laboratory, in Berkeley, California, US. His main research area is electron diffraction and membrane models.

Robert Martin Glaeser
BornJuly 20, 1937
Kenosha, Wisconsin (USA)
Alma materUniversity of California, Berkeley
University of Wisconsin – Madison
Known fordevelopment of cryo-EM
Scientific career
InstitutionsUniversity of California, Berkeley
Lawrence Berkeley National Laboratory
Websitehttp://mcb.berkeley.edu/faculty/all/glaeserr

Glaeser is known[1] for his pioneering work in cryogenic electron microscopy (cryo-EM), where he established how radiation damage was a limiting factor for imaging resolution[2] and how freezing hydrated specimens allowed for more tolerance to radiation damage.[3] He also pushed electron imaging microscopy resolution and contrast by studying the effect of beam-induced movement on the resolution[4] and developed methods for weak-phase imaging.[5]

Glaeser studied at the University of Wisconsin – Madison (B.A. 1959) and the University of California, Berkeley (Ph.D. 1964). He was then a postdoc at the University of Oxford (1963/64) and University of Chicago (1964/65). In 1988/89 he was a visiting scientist at the Max Planck Institute for Biochemistry (MPIB) in Martinsried near Munich, and later a professor at the University of California, Berkeley.

Awards edit

References edit

  1. ^ Lifetime Achievement Awardee – Robert Martin Glaeser – Berkeley Lab
  2. ^ Glaeser, Robert M. (1971). "Limitations to Significant Information in Biological Electron Microscopy as a Result of Radiation Damage". Journal of Ultrastructure Research. 36 (3–4): 466–482. doi:10.1016/S0022-5320(71)80118-1. PMID 5107051.
  3. ^ Glaeser, Robert M.; Taylor, Kenneth A. (1978). "Radiation-Damage Relative to Transmission Electron-Microscopy of Biological Specimens at Low-Temperature". Journal of Microscopy. 112 (1): 127–138. doi:10.1111/j.1365-2818.1978.tb01160.x. PMID 347079. S2CID 45670974.
  4. ^ Henderson, Richard; Glaeser, Robert M. (1985). "Quantitative analysis of image contrast in electron micrographs of beam-sensitive crystals". Ultramicroscopy. 16 (2): 139–150. doi:10.1016/0304-3991(85)90069-5.
  5. ^ Glaeser, R. M. (2013). "Methods for imaging weak-phase objects in electron microscopy". The Review of Scientific Instruments. 84 (11): 111101. doi:10.1063/1.4830355. PMC 3855062. PMID 24289381.
  6. ^ Berkeley Lab Director’s Awards for Lifetime Achievement
  7. ^ 2018 medalists – Glenn T. Seaborg Medal
  8. ^ Robert Glaeser – National Academy of Science