• Sadat Academy for Management Sciences
• School of Advanced Military Studies
• Scottish Association for Marine Science
• South African Mathematical Society
• South African Medical Service
• South African Military Health Service
• South American Mission Society
• Special administrative measure (SAMs)
• Surface-to-air missile (SAMs)
• Syrian American Medical Society

• Sams Publishing

Born before 1950 edit

• William Sams (1792–1871), Australian government official and entrepreneur
• Ferrol Sams (1922–2013), American physician and novelist
• Eric Sams (1926–2004), British musicologist and Shakespeare scholar
• B. J. Sams (television) (born 1935), American local television news personality
• Michael Sams (born 1941), English capital criminal
• B. B. Sams (born 1944), American artist and illustrator
• George W. Sams Jr. (born c. 1946), former field marshal of the American Black Panther Party
• Greg Sams (born 1948), American-British artist, author, inventor; creator of the veggie burger
• John B. Sams (living), American Air Force Lieutenant General and businessman

Born after 1950 edit

• Dallas Sams (1952–2007), American politician
• Jeremy Sams (born 1957), British theatre director, composer and playwright
• Lionel Sams (born 1961), English professional darts player
• Jeffrey D. Sams (born 1964), American television actor
• B.J. Sams (American football) (born 1980), American professional football player
• Pernille Sams (born 1959), Danish real estate agent, lawyer and politician

• Sams, Colorado, a community in the United States

• Mike Sammes (1928–2001), British musician and vocal session arranger