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Sargachromanol

Summary

Sargachromanols are a group of related chemical compounds isolated from the brown alga Sargassum siliquastrum.[1] At least 20 members of the class have been identified, named sargachromanol A through T.[2] Sargachromanol G has in vitro anti-inflammatory effects in isolated mouse macrophage cells.[3]

Sargachromanols

Sargachromanol A

Sargachromanol B

Sargachromanol G
Identifiers
  • A: 856414-50-1 checkY
  • B: 856414-51-2
  • G: 856414-56-7
3D model (JSmol)
  • A: Interactive image
  • B: Interactive image
  • G: Interactive image
ChemSpider
  • A: 9511768
  • B: 9591548
  • G: 9582569
  • A: 11336823
  • B: 11416661
  • G: 11407674
UNII
  • A: 3OG14YJA8B checkY
  • A: CC1=C2C(=CC(=C1)O)CCC(O2)(C)CCC=C(C)CCC=C(C)C=O
  • B: CC1=C2C(=CC(=C1)O)CCC(O2)(C)CCC=C(C)CCC=C(C)CO
  • G: CC1=C2C(=CC(=C1)O)CCC(O2)(C)CCC=C(C)CCC=C(C)C(=O)C(C=C(C)C)O
Properties
A: C22H30O3
B: C22H32O3
G: C27H38O4
Molar mass A: 342.48 g/mol
B: 344.49 g/mol
G: 426.60 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References edit

  1. ^ Jang KH, Lee BH, Choi BW, Lee HS, Shin J (May 2005). "Chromenes from the brown alga Sargassum siliquastrum". Journal of Natural Products. 68 (5): 716–23. doi:10.1021/np058003i. PMID 15921416.
  2. ^ Kang HS, Kim JP (2017). "New Chromene Derivatives with Radical Scavenging Activities from the Brown Alga Sargassum Siliquastrum". Journal of Chemical Research. 41 (2): 116–119. doi:10.3184/174751917X14859570937631. S2CID 100466919.
  3. ^ Yoon WJ, Heo SJ, Han SC, Lee HJ, Kang GJ, Kang HK, et al. (August 2012). "Anti-inflammatory effect of sargachromanol G isolated from Sargassum siliquastrum in RAW 264.7 cells". Archives of Pharmacal Research. 35 (8): 1421–30. doi:10.1007/s12272-012-0812-5. PMID 22941485. S2CID 39748571.