Since being drafted by the organization in 2004, Lewis has played Minor League Baseball as a member of the Mahoning Valley Scrappers, Kinston Indians, Akron Aeros, Buffalo Bisons, and Columbus Clippers. During the 2006 season, Lewis posted a 1.48 ERA, good enough to win the Minor League Baseball ERA title.^{[citation needed]}

Lewis made his first major league appearance against the Baltimore Orioles on September 10, 2008. He threw eight shutout innings, one shy of a complete game, allowing only three hits and no walks while striking out three batters. Lewis continued his dominance in his next start, throwing six shutout innings against the Minnesota Twins, running his scoreless innings streak to 14 to start his career. In total, Lewis started four games for the Tribe, going 4–0 with a 2.63 ERA. For his efforts, Lewis earned the American League Rookie of the Month Award for September 2008.^{[citation needed]}

Lewis was slated to be a member of the Indians' starting rotation for the 2009 season, but was placed on the 15-day disabled list on April 11 with a left elbow strain; he was later transferred to the 60-day disabled list. Lewis was activated from the DL on August 17 and optioned to Triple-A Columbus. He was then outrighted to Columbus on October 30.^{[citation needed]}

Lewis began the 2010 regular season on the Columbus Clippers' roster.^[1] He was released on May 14, 2010.^[2]

• Career statistics and player information from MLB, or ESPN, or Baseball Reference, or Fangraphs, or Baseball Reference (Minors)