The siege of Malacca of 1606 was a military engagement between a Dutch force commanded by Cornelis Matelief and the Portuguese commander André Furtado de Mendonça.

Siege of Malacca
Part of the Dutch–Portuguese War, Malay–Portuguese conflicts
Battle for Malacca between the VOC fleet and the Portuguese, 1606.
Date 1606 Location Portuguese Malacca Result Portuguese victory
Belligerents
Portugal	Dutch Republic Johor Sultanate
Commanders and leaders
André Furtado de Mendonça Martim Afonso de Castro	Cornelis Matelief de Jonge Alauddin Riayat Shah III
Strength
145 men 20 ships	1,500 men 11 ships
Casualties and losses
Unknown	Unknown

The small Portuguese garrison managed to hold out and stop any Dutch direct attacks on the city until additional reinforcements led by Martim Afonso de Castro arrived, which caused the Dutch to retreat from the siege. After they retreated, they were again defeated by the Portuguese at the Battle of Cape Rachado.