The 1576 siege of Mitsuji (Japanese: 三津寺砦の戦い) was part of the eleven-year Ishiyama Hongan-ji War. The Ikkō-ikki, a group of warrior monks and peasants, controlled the fortress and stood as one of the primary obstacles to Oda Nobunaga's bid for power.

Siege of Mitsuji
Part of the Sengoku period
Date May 1576 Location Mitsu-ji, Osaka 34°39′14.04″N 135°30′59.22″E / 34.6539000°N 135.5164500°E / 34.6539000; 135.5164500 Result Ikkō-ikki victory
Belligerents
Ikkō-ikki monks	forces of Oda Nobunaga
Commanders and leaders
Various/Unknown	Oda Nobunaga Harada Naomasa † Niwa Nagahide Hashiba Hideyoshi Takigawa Kazumasu Inaba Ittetsu Hachiya Yoritaka
Strength
15,000 sōhei	3,000 ashigaru
class=notpageimage| Location within Osaka Prefecture Show map of Osaka Prefecture Siege of Mitsuji (Japan) Show map of Japan

In May 1576, Nobunaga personally took part in an attack on the fortress. He led a number of ashigaru (foot soldiers) in pushing back the Ikki garrison to their inner gates. Nobunaga suffered a bullet wound to his leg.^[1] However, Nobunaga lost one of his generals, Harada Naomasa.