Sodium ferric gluconate complex

Summary

Sodium ferric gluconate complex
Clinical data
Trade namesFerrlecit
AHFS/Drugs.comMonograph
MedlinePlusa614030
License data
Routes of
administration
Intravenous (IV)
ATC code
Legal status
Legal status
Identifiers
CAS Number
  • 34089-81-1 checkY
PubChem CID
  • 76968835
DrugBank
  • DB09517
ChemSpider
  • 34989638
UNII
  • CC9149U2QX
KEGG
  • D05859
CompTox Dashboard (EPA)
  • DTXSID80187686 Edit this at Wikidata
Chemical and physical data
FormulaC66H121Fe2NaO65
Molar mass2089.309 g·mol−1
3D model (JSmol)
  • Interactive image
  • O[C@H]([C@@H](O)C(O[Na])=O)[C@H](O)[C@H](O)CO.O[C@H]([C@@H](O)C(O1)=O)[C@H](O)[C@H](O)CO.[Fe]1(OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
  • InChI=1S/5C12H22O11.C6H12O7.2Fe.Na.3O/c5*13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;/h5*4-11,13-20H,1-3H2;2-5,7-11H,1H2,(H,12,13);;;;;;/q;;;;;;2*+3;+1;3*-2/p-1/t5*4-,5-,6-,7-,8+,9-,10+,11-,12+;2-,3-,4+,5-;;;;;;/m111111....../s1
  • Key:MQBDAEHWGRMADS-XNHLMZCASA-M

Sodium ferric gluconate complex, sold under the brand name Ferrlecit, is an intravenously administered iron medication for the treatment of iron deficiency anemia in adults and in children aged six years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy.[2] The macromolecule has an apparent molecular weight of 289,000 – 440,000 Dalton.[3]

The most common side effects in adults are nausea, vomiting and/or diarrhea, injection site reaction, hypotension, cramps, hypertension, dizziness, dyspnea, chest pain, leg cramps, and pain.[2] In children the most common side effects are hypotension, headache, hypertension, tachycardia and vomiting.[2]

References

  1. ^ "Sodium ferric gluconate complex Use During Pregnancy". Drugs.com. 16 December 2019. Retrieved 2 April 2020.
  2. ^ a b c "Ferrlecit- sodium ferric gluconate complex injection". DailyMed. 25 September 2019. Retrieved 2 April 2020.
  3. ^ http://www.drugbank.ca/drugs/DB09517, retrieved 2020-Jun-21

External links

  • "Sodium ferric gluconate complex". Drug Information Portal. U.S. National Library of Medicine.