Sodium glycerophosphate, sold under the brand name Glycophos, is a medication used to supplement phosphate.[3][4] It is administered via intravenous infusion.[3][4]
Clinical data | |
---|---|
Trade names | Glycophos |
AHFS/Drugs.com | Professional Drug Facts |
Pregnancy category |
|
Routes of administration | Intravenous infusion |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number |
|
PubChem CID |
|
DrugBank |
|
ChemSpider |
|
UNII |
|
KEGG |
|
ChEMBL |
|
Chemical and physical data | |
Formula | C3H7Na2O6P |
Molar mass | 216.036 g·mol−1 |
3D model (JSmol) |
|
Melting point | 98 to 100 °C (208 to 212 °F) |
Solubility in water | very soluble |
| |
|
Sodium glycerophosphate is an organic phosphate salt.[3][4]
It was approved for medical use in Australia in November 2019.[5][3][6]
It is an unapproved medication in the United States that was used as a substitute for inorganic phosphate during a drug shortage.[4]
The substance is a mixture of disodium glycerol 1- and 2-phosphates, which have different amounts of water of crystallization; the total amount is 5+1⁄2 H2O per glycerol phosphate molecule. It is a white to off-white powder which may or may not be crystalline, has no discernible odor and tastes salty. It melts at 98 to 100 °C (208 to 212 °F) and decomposes at 130 °C (266 °F). Aqueous solutions have a pH of about 9.5.[7]