St. Mary's Episcopal Church, at 1307 Holmes Street in downtown Kansas City, Missouri, is an Episcopal church in the Anglo-Catholic tradition. It is part of the Diocese of West Missouri.

St. Mary's Episcopal Church
West side of the church
Religion
Affiliation	Episcopal Church in the United States of America
Leadership	The Rev'd Sean C. Kim, SCP, Priest in Charge.
Location
Location	Kansas City, Missouri, United States
Architecture
Architect(s)	William Halsey Wood
Type	Late Gothic Revival
Website
www.stmaryskcmo.org

St. Mary's was the first Episcopal church in Kansas City, established in 1857. The parish was founded as St. Luke's, and the name changed in the 1870s. It was sponsored by Trinity Episcopal Church in Independence, Missouri. Prior to the construction of the building at 13th and Holmes, the congregation worshiped at several locations including a building at 8th and Walnut.

The current Holmes Street building was built in 1887. The Gothic Revival church was accepted into the National Register of Historic Places in 1978.^[1]