Sultopride (trade names Barnetil, Barnotil, Topral) is an atypical antipsychotic of the benzamide chemical class used in Europe, Japan, and Hong Kong for the treatment of schizophrenia.[2][3][4] It was launched by Sanofi-Aventis in 1976.[2] Sultopride acts as a selective D2 and D3 receptor antagonist.[5] It has also been shown to have clinically relevant affinity for the GHB receptor as well, a property it shares in common with amisulpride and sulpiride.[6]
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Trade names | Barnetil, Barnotil, Topral |
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Routes of administration | Oral, IM |
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Pharmacokinetic data | |
Elimination half-life | 3–5 hours |
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ECHA InfoCard | 100.053.293 |
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Formula | C17H26N2O4S |
Molar mass | 354.47 g·mol−1 |
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Site | Ki | Species | Ref |
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D2 | 1.6 | Human | [7] |
D3 | 3.8 | Human | [7] |