Tetraacyldisaccharide 4'-kinase is an enzyme that phosphorylates the 4'-position of a tetraacyldisaccharide 1-phosphate precursor (DS-1-P) of lipopolysaccharide lipid A. This lipid forms outer membranes of Gram-negative bacteria.[1] This enzyme catalyzes the chemical reaction
LpxK | |||||||||
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Identifiers | |||||||||
Symbol | LpxK | ||||||||
Pfam | PF02606 | ||||||||
Pfam clan | CL0023 | ||||||||
InterPro | IPR003758 | ||||||||
OPM superfamily | 124 | ||||||||
OPM protein | 4ehx | ||||||||
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tetraacyldisaccharide 4'-kinase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.1.130 | ||||||||
CAS no. | 107309-06-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor.