TiGenix

Summary

TiGenix is a European cell therapy company with a proprietary validated allogeneic expanded adipose-derived stem cell (eASC) platform technology for the treatment of autoimmune and inflammatory diseases, and a commercialized product. Its corporate headquarters are in Leuven, Belgium, and it has operations in Madrid, Spain. TiGenix was founded in 2000 by Prof. Dr. Frank P. Luyten and Gil Beyen as a spin-off from the Katholieke Universiteit Leuven and the Ghent University.[citation needed]

TiGenix NV
Company typePublic (euronext: TIG)
IndustryBiotechnology
Founded2000
HeadquartersLeuven, Belgium
Key people
Eduardo Bravo, CEO
Number of employees
70
Websitehttp://www.tigenix.com

TiGenix's therapeutic approach is to focus on the use of living cells rather than conventional drugs for the treatment of inflammatory and autoimmune diseases, through its eASC-based platform, and heart disease, through its CSC-based platform. TiGenix's pipeline of stem cell programs is based on validated platforms of allogeneic stem cells.[citation needed]

History edit

TiGenix has completed and received positive data in, a single pivotal Phase III trial in Europe of its most advanced product candidate Cx601, a potential first-in-class injectable allogeneic stem cell therapy indicated for the treatment of complex perianal fistulas in patients with Crohn's disease. On 28 July 2016 The Lancet published the results of their phase 3 ADMIRE-CD Trial.[1]

Acquisition by Takeda edit

In early January 2018, Takeda Pharmaceutical Company announced it would acquire TiGenix for up to €520 million ($632 million).[2]

References edit

  1. ^ "The Lancet of publishes 24-Week Results of the Phase 3 ADMIRE-CD Trial Investigating Cx601 in the Treatment of Complex Perianal Fistulas in Patients with Crohn's Disease". {{cite journal}}: Cite journal requires |journal= (help)
  2. ^ "Takeda to Acquire TiGenix for €520M". 5 January 2018.

External links edit

  • TiGenix website
  • 'Tigenix has been a rollercoaster', De Tijd, 14 May 2014
  • Kanaal Z report, July 2014 on YouTube
  • 'Cx601 could be launched in 2017', L'Echo, 3 July 2014
  • TiGenix on Kanaal Z television on YouTube
  • TiGenix at Alliance for Regenerative Medicine meeting, March 2015 on YouTube