Tilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer.[2] It is used as an antiviral drug in some countries which do not require double-blind placebo-controlled studies, including Russia. It is effective against Ebola virus in mice.[3]
Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | By mouth (tablets) |
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Pharmacokinetic data | |
Bioavailability | 60% |
Protein binding | ~80% |
Metabolism | Nil |
Elimination half-life | 48 hours |
Excretion | Feces (70%), urine (9%)[1] |
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PubChem CID |
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ChemSpider |
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UNII |
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KEGG |
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ChEBI |
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ChEMBL |
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CompTox Dashboard (EPA) |
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Chemical and physical data | |
Formula | C25H34N2O3 |
Molar mass | 410.558 g·mol−1 |
3D model (JSmol) |
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Tilorone activates the production of interferon.[2]