Triflunordazepam

Summary

Triflunordazepam (also known as Ro5-2904)[1] is a drug which is a benzodiazepine derivative with high GABAA receptor affinity, and has anticonvulsant effects.[2][3]

Triflunordazepam
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number
  • 2285-16-7 checkY
PubChem CID
  • 16795
ChemSpider
  • 15920
UNII
  • 8CS486VL3D
CompTox Dashboard (EPA)
  • DTXSID70177394 Edit this at Wikidata
Chemical and physical data
FormulaC16H11F3N2O
Molar mass304.272 g·mol−1
3D model (JSmol)
  • Interactive image
  • C1C(=O)NC2=C(C=C(C=C2)C(F)(F)F)C(=N1)C3=CC=CC=C3
  • InChI=1S/C16H11F3N2O/c17-16(18,19)11-6-7-13-12(8-11)15(20-9-14(22)21-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,21,22)
  • Key:UUBMOUNXQFMBQF-UHFFFAOYSA-N
  (verify)

See also edit

References edit

  1. ^ DE 1136709 
  2. ^ "Ro5-2904". Archives Internationales de Pharmacodynamie et de Thérapie. 154: 131. 1965.
  3. ^ So SS, Karplus M (December 1996). "Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors". Journal of Medicinal Chemistry. 39 (26): 5246–56. doi:10.1021/jm960536o. PMID 8978853.