Real crimes such as the spider burglar, VCD piracy, juvenile delinquency, gangsterism and cybercrime have been woven into this 25-episode action story. The police officers in the story stay alert daily to provide security to the civilians, making them the "True Heroes".

Chen Junhao (Christopher Lee) is a righteous and courageous police officer who graduated with top honours from the police academy and harbours the ambition to follow his father Chen Rongyao's (Moses Lim) footsteps into the elite Criminal Investigation Department. He is sorely disappointed when he learns that he has been assigned to a neighbourhood police centre. At the NPC, Junhao and his colleague Wang Feng (Allan Wu) do not see eye to eye and their relationship further deteriorates when Junhao accidentally mistakes Wang Feng's father Wang Jiancheng (Huang Wenyong) for a burglar and "arrests" him because he was merely asking his wife Zhong Xiaolan (Lin Meijiao) for money but she refused to give him money anymore because he was extremely addicted to gambling and owed lots of money to multiple loan sharks. As a result, to no avail, he went on to attempt burglary and stole money at the Wang family's home.

During a big fire, Junhao saves the life of an old lady (Li Yinzhu), earning the adoration of the old lady's granddaughter, Irene (Yvonne Lim), who is the neighbourhood "ah lian". Much to Junhao's annoyance, Irene tries to come between him and his colleague-cum-love-interest, Cai Kexin (Phyllis Quek).

Wang Feng falls for Junhao's younger sister Chen Huimin (Jeanette Aw), a nurse working at a government hospital and attempts to patch up his relationship with his younger brother Wang Wei (Zen Chong). He eventually changes his mind about Junhao when the latter saves him during a mission. Junhao also accepts Wang Feng after uncovering his troubled and complex family life.

Junhao's best friend Wu Zhiguang (Cavin Soh) uses his identity to commit multiple sex crimes and Junhao ends up taking the rap and is jailed. Kexin's younger sister Cai Kejuan (Zhang Chunmei) has been kidnapped by Irene as revenge against her for causing the latter's grandmother's death in a traffic accident. Wang Feng witnesses the stabbing of Wang Wei, who eventually dies in the hands of a loan shark named Hui-ge (Ye Shipin), whom is an enemy of Jiancheng and wanted to take revenge on both him and his younger son Wang Wei. Each officer is tested as their jobs soon catch up with their personal lives.

At the end, Huimin eventually resigns as nurse and joins the Singapore Police Force as a police officer, where she becomes a Sergeant, whereas Kexin gets promoted to Staff Sergeant.

• Christopher Lee as SGT Chen Junhao
• Phyllis Quek as SGT Cai Kexin, later promoted to SSGT and becomes SSGT Cai Kexin
• Allan Wu as SSGT Wang Feng
• Yvonne Lim as Irene (Villain but repented at the end)
• Jeanette Aw as Chen Huimin (Chen Junhao's younger sister), works as a nurse at a government hospital but later resigns and joins the Singapore Police Force as a police officer and becomes SGT Chen Huimin
• Moses Lim as Chen Rongyao (Chen Junhao's father), formerly a police officer from Criminal Investigation Department, later retired and currently working as a taxi driver and also as the leader of the Neighbourhood watch group
• Zen Chong as Wang Wei (Wang Feng's younger brother)
• Cavin Soh as Wu Zhiguang (Chen Junhao's best friend) (Villain but repented)
• Huang Wenyong as Wang Jiancheng (Wang Feng's father) (Villain but repented at the end)
• Lin Meijiao as Zhong Xiaolan (Wang Feng's mother)
• Alan Tern as CPL Jiang Yijie
• Li Wenhai as ASP Ge Ming
• Jin Yinji as Chen Meizhen (Cai Kexin's mother)
• Chen Guohua as SGT Liu Zhenyang
• Shaun Chen as Zhang Hanliang
• Ye Shipin as Hui-ge (loan shark) (Main Villain of the series)
• Joey Ng as Esther (Villain but repented)
• Gary Yap as Mike (Main Villain of the series)
• Li Yinzhu as Irene's grandmother
• Zhang Yaodong as Peter (CID officer)
• Zhang Chunmei as Cai Kejuan (Cai Kexin's younger sister)

• "True Heroes". Archived from the original on 28 May 2008.
• True Heroes (English)