Unc-51-like kinase 2 (C. elegans) also known as ULK2 is an enzyme which in humans is encoded by the ULK2 gene.[1] The gene is located within the Smith–Magenis syndrome region on chromosome 17.
unc-51-like kinase 2 (C. elegans) | |||||||
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Identifiers | |||||||
Symbol | ULK2 | ||||||
NCBI gene | 9706 | ||||||
HGNC | 13480 | ||||||
OMIM | 608650 | ||||||
RefSeq | NM_014683 | ||||||
UniProt | Q8IYT8 | ||||||
Other data | |||||||
EC number | 2.7.11.1 | ||||||
Locus | Chr. 17 p11.2 | ||||||
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This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain.[2] ULK2 and the GTPase activating protein SynGAP function cooperatively in axon formation.[3]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.