USS Little Brothers (SP-921) was a United States Navy tug in commission from 1917 to 1919.

History
United States
Name	USS Little Brothers
Namesake	Previous name retained
Builder	George Bishop, Patchogue, New York
Completed	1910
Acquired	Acquired 21 July 1917 Delivered 13 August 1917
Commissioned	20 August 1917
Decommissioned	14 August 1919
Fate	Returned to owner 26 August 1919
Notes	Operated as commercial fishing vessel Little Briothers 1910-1917 and from 1919
General characteristics
Type	Tug
Tonnage	30 Gross register tons
Length	70 ft (21 m)
Beam	17 ft 5 in (5.31 m)
Draft	5 ft 9 in (1.75 m)
Speed	10 knots
Complement	8
Armament	None

Little Brothers was built as a commercial fishing vessel of the same name in 1910 by George Bishop at Patchogue, New York. On 21 July 1917, the U.S. Navy chartered her from her owner, John C. Doxsee of Islip, New York, for use as a tug during World War I. Assigned the section patrol number 921, she was enrolled in the Naval Coast Defense Reserve on 3 August 1917, delivered to the Navy on 13 August 1917, and commissioned at New York City as USS Little Brothers (SP-921) on 20 August 1917.

Assigned to the 3rd Naval District and based at New York City, Little Brothers was employed in carrying military supplies and ammunition for the rest of World War I and into 1919. She operated in the East River, New York Harbor, Gravesend Bay, Jamaica Bay, and Long Island Sound.

Little Brothers was decommissioned on 14 August 1919. She was returned to Doxsee on 26 August 1919.