USS Sequoyah (SP-426), later USS SP-426, was a United States Navy patrol vessel in commission from 1917 to 1919.

History
United States
Name	USS Sequoyah (1917-1918) USS SP-426 (1918-1919)
Namesake	Sequoyah was her previous name retained SP-426 was her section patrol number
Builder	Crockett, Pocomoke City, Maryland
Completed	1907
Acquired	24 August 1917
Commissioned	24 August 1917
Decommissioned	29 January 1919
Fate	Returned to owner 29 January 1919
Notes	Operated as private motorboat Sequoyah 1907-1917 and from 1919
General characteristics
Type	Patrol vessel
Tonnage	15 gross register tons
Length	60 ft (18 m)
Beam	16 ft (4.9 m)
Draft	5 ft 3 in (1.60 m)
Speed	8 knots
Complement	6
Armament	1 × 1-pounder gun

Sequoyah was built as a private motorboat of the same name in 1907 by Crockett of Pocomoke City, Maryland. On 24 August 1917, the U.S. Navy chartered her from her owner, Albert T. Lavallette of Hampton, Virginia, for use as a section patrol boat during World War I. She was commissioned as USS Sequoyah (SP-426) the same day.

Sequoyah was used for transporting ammunition and supplies in the harbor at Norfolk, Virginia, for the rest of World War I. In 1918, she was renamed USS SP-426.

SP-426 was decommissioned and returned to her owner on 29 January 1919.